References

Asano Y, Okamura S et al. Effect of epigallocatechin gallate on leukemic blast cells from patients with acute myeloblastic leukemia. Life Sci 1997; 60:135-42

Challa A et al. Interactive suppression of aberrant crypt foci induced by azoxymethane in rat colon by phytic acid and green tea. Carcinogenesis 1997; 10:2023-26

Chen ZP, et al. Green tea epigallocatechin gallate shows a pronounced growth inhibitory effect on cancerous cells but not on their normal counterparts. Cancer Lett 1998; 129:173-79

Chung FL et al. Inhibition of lung carcinogenesis by black tea in Fischer rats treated with a tobacco-specific carcinogen: Caffeine as an important constituent. Cancer Res 1998;58:4096-4101

Deng ZY, Tao BY, et al. Effect of green tea and black tea on blood glucose, triglycerides, and antioxidants in aged rats. J Agricult Food Chem 1998;46:3875-78

Francheschi S et al. Influence of food groups and food diversity on breast cancer risk in Italy. Int J Cancer 1995; 63:785-89

Hara Y. Influence of tea catechins on the digestive tract. J Cel Biochem 1997; Suppl 27: 52-58

Hibasami H et al. Induction of apoptosis in human stomach cancer cells by green tea catechins. Oncol Repetition 1998; 5:527-29

Hirose M et al. Inhibition of mammary gland carcinogenesis by green tea catechins and other naturally occurring antioxidants in female Sprague-Dawley rats pretreated with MDBA. Cancer Lett 1994; 83:149-56

Inoue M, Tajima K, et al. Tea and coffee consumption and the risk of digestive tract cancers: data from a comparative case-referent study in Japan. Cancer Causes Control 1998;9:209-16

Ito Y et al. Chromosome aberrations induced by aflatoxin B1 in rat bone marrow cells in vivo and their suppression by green tea. Mutat Res 1989; 222:253-61

Katiyar SK, Mukhtar H. Tea antioxidants in cancer chemoprevention. J Cell Biochem Suppl 1997; 27:59-67

Katiyar SK et al. Polyphenolic antioxidant epigallocatechin gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin. Photochem Photobiol 1999; 69:148-53

Khafif A; Schantz SP, et al. Quantitation of chemopreventive synergism between epigallocatechin gallate and curcumin in normal, premalignant, and malignant oral epithelial cells. Carcinogenesis 1998;19:419-24

Komori A, Yasunami J, et al. Anticarcinogenic activity of green tea polyphenols. Jpn J Clin Oncol 1993; 23:186-90

Kuroda Y, Hara Y. Antimutagenic and anticarcinogenic activity of tea polyphenols. Mutat Res 1999; 436:69-97

Lean ME et al. Dietary flavonols protect diabetic human lymphocytes against oxidative damage to DNA. Diabetes 1999; 48:176-81

Lee IP et al. Chemopreventive effects of green tea against cigarette smoke-induced mutations in humans. J Cell Biochem 1997; Suppl 27:68-75

Liao S, Hipakka RA. Selective inhibition of steroid 5-alpha-reductase isozymes by tea epicatechin-3-gallate and epigallocatechin-3-gallate. Biochem Biophys Res Commun 1995;214:833-38

Liao S, Umekita Y et al. Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate. Cancer Lett 1995; 96:239-43

Lin YL, Cheng CY, et al. Hypolipidemic effect of green tea leaves through induction of antioxidant and phase II enzymes including superoxide dismutase, catalase, and glutathione S-transferase in rats. J Agricult Food Chem 1998;46:1893-99

Lu LH, Lee SS, Huang HC. Epigallocatechin suppression of proliferation of vascular smooth muscle cells: correlation with c-jun and JNK. Brit J Pharmacol 1998;124:1227-37

McCarty MF. Polyphenol-mediated inhibition of AP-1 transactivating activity may slow cancer growth by impeding angiogenesis and tumor invasiveness. Med Hypoth 1998; 50:511-14

Morre D, Morre DJ. Findings on epigallocatechin gallate and tNOX inhibition presented at the 38th annual meeting of the American Society for Cell Biology; summary available at http//www.uns.purdue.edu

Naasani I et al. Telomerase inhibition, telomere shortening, and senescence of cancer cells by tea catechins. Biochem Biophys Res Commun 1998; 249:391-96

Nagata C et al. Associations of coffee, green tea, and caffeine intakes with serum concentrations of estradiol and sex hormone-binding globulin in premenopausal Japanese women. Nutr Cancer 1998; 30:21-24

Nakachi K, Suemasu K, et al. Influence of drinking green tea on breast cancer malignancy among Japanese patients. Jpn J Cancer Res 1998;89:254-61

Oguri A et al. Inhibitory effects of antioxidants on formation of heterocyclic amines. Mutat Res 1998; 402:237-45

Otsuka T, Ogo T, et al. Growth inhibition of leukemic cells by epigallocatechin gallate, the main constituent of green tea. Life Sciences 1998; 63:1397-1403

Parshad R, Sanford RR, et al. Protective action of plant polyphenols on radiation-induced chromatid breaks in cultured human cells. Anticancer Res 1998;18:3263-66

Pashka AG et al. Induction of apoptosis in prostate cancer cell lines by the green tea component, epigallocatechin gallate. Cancer Lett 1998;130:1-7

Quin G et al. Inhibition of aflatoxin B1-induced initiation of hepatocarcinogenesis in the rat by green tea. Cancer Lett 1997; 112:149-54

Reuters. Green tea blocks angiogenesis. Internet Health News, 3-31-1999 Sai I, Kai S et al. Protective effects of green tea on hepatotoxicity, oxidative DNA damage and cell proliferation in the rat liver, induced by repeated oral administration of 2-nitropropane. Food Chem Toxicol 1998; 6:1043

Sazuka M, Imazawa H, et al. Inhibition of collagenases from mouse lung carcinoma cells by green tea catechins and black tea theaflavins. Biosci Biotechnol Biochem 1997; 61:1504-06

Suganuma M, Okabe S, et al. Synergistic effects of epigallocatechin gallate with epicatechin, sunlilndac, or tamoxifen on cancer-preventive activity in the human lung cancer cell line PC-9. Cancer Res 1999;59:44-7

Sugiyama T, Sadzuka Y. Combination of theanine with doxorubicin inhibits hepatic metastasis of M5076 ovarian sarcoma. Clin Cancer Res 1999; 5:413-16 Sugiyama T, Sadzuka Y. Enhancing effects of green tea components on the antitumor activity of adriamycin against M5076 ovarian sarcoma. Cancer Lett 1998; 133:19-26

Valcic S et al. Inhibitory effect of six green tea catechins and caffeine on the growth of four selected human tumor cell lines. Anticancer Drugs 1996; 7:461-68

Yamane T, Nakatsni H et al. Inhibitory effects and toxicity of green tea polyphenols for gastrointestinal carcinogenesis. Cancer 1996;77(suppl):1662-67

Yan YS. Effect of Chinese tea extract on the immune function of mice bearing tumors and their antitumor activity. Chung Hua Yu Fang 1992; 26:5-7

Yang FJ et al. Green tea polyphenols block endotoxin-induced tumor necrosis factor alpha production and lethality in murine model. J Nutr 1998; 128:2334-40

Yang GY, Liao J, et al. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols. Carcinogenesis 1998; 19:611-16

Zhen Y et al. Green tea extract inhibits nucleoside transport and potentiates the antitumor effect of antimetabolites. Chin Med Sci 1991; 6:1-5

Zhu BT, Taneja N et al. Effects of tea polyphenols and flavonoids on liver microsomal glucuronidation of estradiol and estrone. J Steroid Biochem Mol Biol 1998;64:207-15

Anderson JW et al. Selective effects of different antioxidants on oxidation of lipoproteins from rats. Proc Soc Exp Biol Med 1998;218:376-81.

Bravo L, Abia R et al. Degradation of polyphenols (catechin and tannic acid) in the rat intestinal tract. Effect on colonic fermentation and fecal output. Br J Nutr 1994;71:933-46.

Chan MM et al. Inhibition of inducible nitric oxide synthese gene expression and enzyme activity by epigallocatechin gallate, a natural product from green tea. Biochem Pharmacol 1997; 54:1281-86.

Chen ZY, Chan PT. Antioxidant activity of green tea catechins in canola oil. Chem Phys Lipids 1996; 82:163-72.

Choi JH et al. Effects of green tea catechins on hepatic microsomal phospholipase. J Nutr Sci Vitaminol 1998; 44:673-83.

Chung HY et al. Peroxynitrite-scavenging activity of green tea tannin. J Agric Food Chem 1998; 46:4484-86.

Deng ZY, Tao BY, et al. Effect of green tea and black tea on blood glucose, triglycerides, and antioxidants in aged rats. J Agricult Food Chem 1998;46:3875-78.

Gomes A et al. Anti-hyperglycemic effect of black tea (Camellia sinensis) in rat. J Ethnopharmacol 1995; 45: 223-26.

Guo Q et al. Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes. Biochim Biophys Acta 1996; 1304:210-22.

Hara Y. Influence of tea catechins on the digestive tract. J Cel Biochem 1997; Suppl 27: 52-58.

Hayashi M et al. Effects of green tea extract on galactosamine-induced hepatic injury in rats. Nippon Yakurigaku Zasshi 1992; 100:391-99.

Huang Y, Zhang AQ, et al. Vasorelaxant effects of purified green tea catechin derivatives in rat mesenteric artery. Life Sciences 1998;63:275-283.

Imai K, Nakachi K. Cross-sectional study of effects of drinking green tea on cardiovascular and liver diseases. BMJ 1995;310:693-96.

Kabuto H et al. Monoamine metabolites, iron induced seizures, and the anticonvulsant effects of tannins. Neurochem Res 1992; 6:585-90.

Kaneko T, Matsuo M, Baba N. Inhibition of linoleic acid hydroperoxide-induced toxicity in cultured human umbilical vein endothelial cells by catechins. Chem Biol Interact 1998; 114:109-19.

Karawya Ms. Et al. Diphenylamine, an antihyperglycemic agent from onion and tea. J Natural Prod 1984; 47:775-80.

Keli SO et al. Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study. Arch Intern Med 1995; 156:637-42.

Kreydiyyeh SI et al. Tea extract inhibits intestinal absorption of glucose and sodium in rats. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 1994;108:359-65.

Lean ME et al. Dietary flavonols protect diabetic human lymphocytes against oxidative damage to DNA. Diabetes 1999; 48:176-81.

Lin AM et al. The antioxidant property of green tea against iron-induced oxidative stress in rat brain. Chin J Physiol 1998; 41:189-94.

Lin YL, Lin JK. Epigallocatechin gallate blocks the induction of nitric oxide synthase by downregulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB. Mol Pharmacol 1997; 52:465-72.

Lu LH, Lee SS, Huang HC. Epigallocatechin suppression of proliferation of vascular smooth muscle cells: correlation with c-jun and JNK. Brit J Pharmacol 1998;124:1227-37.

Matsuoka Y et al. Ameliorative effects of tea catechins on active oxygen-related nerve cell injuries. J Pharmacol Exp Ther 1995; 274:602-8.

Mazzio EA et al. Food constituents attenuate monoamine oxidase activity and peroxide levels in C6 astrocyte cells. Planta Med 1998;64:603-6.

Nakane H, Ono K. Differential inhibition of HIV reverse transcriptase and varius DNA and RNA polymerases by some catechin derivatives. Nucleic Acids Symp Ser 1989; (21): 115-16.

Nakao M, Takio S, Ono K. Alkyl peroxyl radical scavenging activity of catechins. Phytochemistry 1998;49:2379-82.

Pannala AS et al. Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols. Biochem Biophys Res Commun 1997; 232:164-68.

Parshad R, Sanford RR, et al. Protective action of plant polyphenols on radiation-induced chromatid breaks in cultured human cells. Anticancer Res 1998;18:3263-66.

Pietta P, Simonetti P. Dietary flavonoids and interactions with endogenous antioxidants. Biochem Molec Biol International 1998;44:1069-74.

Plumb GW et al. Antioxidant properties of catechins and proanthocyanidins: effect of polymerization, galloylation and glycosylation. Free Radic Res 1999; 29:351-58.

Quinlan P, Lane J, Aspinall L. Effects of hot tea, coffee and water ingestion on physiological responses and mood: the role of caffeine, water, and beverage type. Psychopharmacology 1997; 134:164-73.

Rasheed A, Haider M. Antibacterial activity of Camellia sinensis extracts against dental caries. Arch Pharm Res 1998;21:348-52.

Sanaka S, Aizawa M, et al. Inhibitory effect of green tea polyphenols on growth and adherence of an oral bacterium, Porphyromonas gingivalis. Biosci Biotechnol Biochem 1996; 60:745-49.

Sato Y et al. Possible contribution of green tea drinking habits to the prevention of stroke. Tohoku J Exp Med 1989; 157:337-43.

Serafini M et al. In vivo antioxidant effect of green and black tea in man. Eur J Clin Nutr 1996;50:28-32.

Soliman KF, Mazzio EA. In vitro attenuation of nitric oxide production in C6 astrocyte cell culture by various dietary compounds. Proc Soc Exp Biol Med 1998; 218:390-97.

Takabayashi F, Harada N. Effects of green tea catechins on cerulein-induced acute pancreatitis in rats. Pancreas 1997; 14:276-79.

Tao P. The inhibitory effects of catechin derivatives on the activities of human immunodeficiency virus reverse transcriptase and DNA polymerases. Chung Kuo 1992; 14:334-38.

Uchida S et al. Effect of epigallocatechin gallate on the life span of stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol 1995; Suppl 1: S302-3.

Vinson JA, Dabbagh YA. Tea phenols: antioxidant effectiveness of teas, tea components, tea fractions and their binding with lipoproteins. Nutr Res 1998; 18:1067-75.

Vinson JA, Dabbagh YA. Effect of green and black tea supplementation on lipids, lipid oxidation and fibrinogen in the hamster: mechanisms for the epidemiological benefits of tea drinking. FEBS Let 1998; 433:44-46.

Wang H, Wu Y. Inhibitory effect of Chinese tea on N-nitrosation in vitro and in vivo. IARC Sci Publ 1991; 105:546-49.

Yang FJ et al. Green tea polyphenols block endotoxin-induced tumor necrosis factor alpha production and lethality in murine model. J Nutr 1998; 128:2334-40.

Yang TT, Koo MW. Hypocholesterolemic effects of Chinese tea. Pharmacol Res 1997; 35:505-12.

Yokogoshi H et al. Effect of theanine, r-glutamylethylamide, on brain monoamines and striatal dopamine release in conscious rats. Neurochem Res 1998; 23:667-73.

Yokozawa T et al. In vivo and in vitro studies on the radical scavenging activity of tea. J Agric Food Chem 1998; 46:2143-50.

You S. Study on feasibility of Chinese green tea polyphenols for preventing dental caries. Chung Hua Kou Chiang 1993; 28:197-9.

Zhang J, Kashket S. Inhibition of salivary amylase by black and green teas and their effects on the intraoral hydrolysis of starch. Caries Res 1998: 32:233-38.

Zhao BL et al. Scavenging effect of extracts of green tea and natural antioxidants on active oxygen species. Cell Biophys 1989; 14:175-85.